Frastim 300 Mcg Injection

Description

Frastim 300 Mcg Injection (Filgrastim)

Generic Name:

The generic name for Frastim 300 mcg Injection is Filgrastim.

Equivalent Brand in the USA:

Neupogen

Overview of Frastim 300 Mcg Injection (Filgrastim)

Frastim 300 mcg Injection contains Filgrastim, a human granulocyte colony-stimulating factor (G-CSF) analog. It aids in stimulating white blood cell growth and reduces the risk of infections in patients undergoing chemotherapy. Those with blood disorders should not use this medication. It is available only through a doctor’s prescription at leading pharmacies, drugstores, and medical supply outlets.

Manufacturer:

Manufactured by RPG Life Sciences Ltd., a prominent pharmaceutical company.

Strength:

Each Frastim 300 mcg Injection contains 300 mg of Filgrastim and is also available in various other substitutes at major pharmacies and online stores.

Indications for Use:

Frastim 300 mcg Injection is used to treat:

• Neutropenia due to chemotherapy
• Bone Marrow Transplantation
• Peripheral Progenitor Cell Transplantation
• Chronic Neutropenia
• Neutropenia resulting from radiation

Mechanism of Action:

Filgrastim in Frastim 300 mcg Injection stimulates bone marrow to produce white blood cells, which help protect against infections. As a G-CSF analog produced through recombinant DNA technology, Filgrastim controls the growth of progenitor cells and their maturation into neutrophils. It also accelerates the release of neutrophils from bone marrow, shortening the time needed for maturation, thereby enhancing their ability to combat infections. This can lead to faster recovery of neutrophils in patients receiving chemotherapy, reducing the duration of neutropenia.

Precautions Before Use:

Ensure that:

• You are not allergic to Filgrastim
• You do not have any serious medical conditions
• Your doctor is informed of your medical history, including any previous diseases, surgeries, medications, supplements, and lifestyle choices.

Avoid While Taking Frastim 300 Mcg Injection:

• Alcohol consumption
• Driving
• Taking medications without a prescription

Contraindications:

Do not use Frastim 300 mcg Injection if you:

• Have a history of allergy or hypersensitivity
• Have liver or kidney issues
• Have experienced splenic rupture
• Have Acute Respiratory Distress Syndrome (ARDS)
• Are experiencing a sickle cell crisis
• Have a blood disorder
• Have decreased bone density
• Are pregnant or breastfeeding
• Have existing infections

Notify Your Doctor If You:

• Have any allergies related to the injection
• Are consuming alcohol or other drugs
• Have liver disease
• Have any infections

Dosage Instructions:

Frastim 300 mcg Injection is used to treat infections after chemotherapy. It is available in various strengths and substitutes and must be obtained through a doctor’s prescription. Always consult your physician regarding the appropriate dosage and timing as these may vary based on age and the severity of the condition.

Adults should take the injection at a consistent time with or without food, as directed by the doctor. It is essential to take the injection regularly for optimal results.

Dosage Guidelines:

As Frastim 300 mcg Injection comes in multiple strengths and forms, always follow your doctor’s specific instructions regarding dosage. Do not self-administer or exceed the recommended duration of use.

Administration:

Frastim 300 mcg Injection should be administered at a consistent time as per your doctor’s advice. It should only be given by a healthcare professional, not self-administered.

Duration of Use:

Always use Frastim 300 mcg Injection as prescribed. Do not begin or stop treatment on your own. Follow all instructions from your doctor regarding dosage and duration.

In Case of Overdose:

Seek emergency medical assistance or contact your healthcare provider immediately if overdose symptoms occur. Given that Frastim 300 mcg Injection is administered by a qualified professional, the risk of overdose is low. However, your physician will take immediate action if they notice any symptoms of overdose.

Missed Dose:

If you miss a dose, it should be administered by your healthcare provider as soon as possible. If it’s close to the time of your next scheduled dose, skip the missed dose. Do not double up on doses. Since this injection is given by a professional, the chances of a missed dose are minimal.

Possible Side Effects:

• Bone pain
• Weakness
• Headache
• Rash
• Nausea
• Increased lactate dehydrogenase levels in the blood
• Vomiting
• Increased uric acid levels in the blood
• Oropharyngeal pain
• Hair loss
• Fatigue
• Diarrhea
• Constipation
• Decreased appetite
• Cough
• Difficulty breathing
• Abdominal pain
• Fever and chills
• Weight loss
• Swelling or inflammation of the mouth

Common Drug Interactions:

Several medications may interact with Frastim 300 mcg Injection, potentially causing adverse effects or reducing effectiveness. Always inform your doctor about any other prescriptions or supplements you are taking. Known interactions include:

• Cisplatin
• Fluorouracil
• Doxorubicin

Interactions with specific disease conditions include:

• Glomerulonephritis
• Myeloid Tumors
• Leukocytosis

Warnings and Precautions:

Frastim 300 mcg Injection may exacerbate certain conditions, including:

• Allergic reactions
• Kidney or liver disease
• Pregnancy or breastfeeding
• Driving or operating heavy machinery due to potential dizziness
• Staying well-hydrated during treatment
• Regular monitoring of bone density and blood tests is recommended during treatment
• Consult your doctor immediately if you experience any of the aforementioned conditions.

Important Reminders:

• Keep Frastim 300 mcg Injection out of the reach of children.
• Use this medication cautiously in children.
• Not recommended for pregnant women due to potential risks to the fetus.
• Review the information provided with the medication carefully.
• Consult your healthcare provider if you have any uncertainties regarding dosage, timing, or strength.

Storage:

Store Frastim 300 mcg Injection at room temperature in a dark and dry place. Ensure the injection is intact and undamaged at the time of purchase and storage.