Grafeel 300 Mcg Injection

Description

Grafeel 300 Mcg Injection (Filgrastim)

Generic Name for Grafeel 300 Mcg Injection:

The generic name for Grafeel 300 mcg Injection is Filgrastim.

Equivalent USA Brand to Grafeel 300 Mcg Injection (Filgrastim):

• Neupogen

Overview of Grafeel 300 Mcg Injection (Filgrastim)

Grafeel 300 mcg Injection contains Filgrastim, which is a human granulocyte colony-stimulating factor (G-CSF) analog. Filgrastim is essential in promoting the growth of white blood cells, reducing the risk of infection for patients undergoing chemotherapy. This medicine is available only through a doctor’s prescription and should not be used by patients with blood disorders.

Manufacturer:

Grafeel 300 mcg Injection is manufactured by Dr. Reddy’s Laboratories Ltd., a prominent pharmaceutical company.

Dosage Strength:

Each Grafeel 300 mcg Injection contains 300 mg of Filgrastim as its active ingredient. It is available in various formulations at leading pharmacies and online stores.

Uses of Grafeel 300 Mcg Injection (Filgrastim):

This injection is used to treat the following conditions:

• Neutropenia caused by chemotherapy
• Bone marrow transplantation
• Peripheral progenitor cell transplantation
• Chronic neutropenia
• Neutropenia resulting from radiation exposure

Mechanism of Action:

Filgrastim stimulates the bone marrow to produce white blood cells that protect against infections. It is produced through recombinant DNA technology and helps increase neutrophil levels in patients receiving cytotoxic chemotherapy.

Precautions Before Use:

Ensure that:

• You are not allergic to Filgrastim.
• You do not have any serious health conditions.
• Your doctor is aware of your medical history, including existing diseases, surgeries, and medications.

What to Avoid While Using Grafeel 300 Mcg Injection (Filgrastim):

• Avoid consuming alcohol.
• Avoid driving or operating heavy machinery.
• Avoid taking medications without a prescription.

When Not to Use Grafeel 300 Mcg Injection (Filgrastim):

You should avoid this injection if you:

• Have a history of allergies or hypersensitivity.
• Have liver or kidney issues.
• Have experienced a splenic rupture.
• Have acute respiratory distress syndrome (ARDS).
• Have sickle cell crisis.
• Have any blood disorders.
• Have reduced bone density.
• Are pregnant or breastfeeding.
• Are taking alcohol or other medications.
• Have a liver condition.

Dosage Instructions:

Grafeel 300 mcg Injection should be administered under medical supervision. The dosage may vary based on individual health conditions and should be prescribed by a physician.

Adults should take the injection at consistent times, with or without food, as advised by their doctor. Regular administration is crucial for optimal results.

Dosage Guidelines:

Since Grafeel 300 mcg Injection comes in various forms, patients must adhere strictly to their doctor’s prescriptions and not self-medicate.

Administration of Grafeel 300 Mcg Injection (Filgrastim):

Follow your doctor’s instructions regarding the timing and method of administration. Only qualified healthcare professionals should administer this injection.

Duration of Treatment:

Always use Grafeel 300 mcg Injection as directed by your doctor. Do not modify the dosage or duration without consulting a healthcare provider.

Overdose Management:

In case of overdose symptoms, seek immediate medical attention. Given that this injection is administered in clinical settings, the chances of overdose are minimal.

Missed Dose Protocol:

If a dose is missed, contact your doctor for guidance on the next steps. Do not double the dosage to compensate for a missed one. The administration of this injection is typically supervised in a clinical setting, reducing the likelihood of missed doses.

Potential Side Effects of Grafeel 300 Mcg Injection (Filgrastim):

• Bone pain
• Weakness
• Headaches
• Rash
• Nausea
• Increased blood lactate dehydrogenase levels
• Vomiting
• Elevated uric acid levels
• Throat pain
• Hair loss
• Fatigue
• Diarrhea
• Constipation
• Loss of appetite
• Cough
• Difficulty breathing
• Stomach pain
• Fever and chills
• Weight loss
• Swelling or inflammation in the mouth

Common Drug Interactions:

Several medications may interact with Grafeel 300 mcg Injection, potentially causing adverse effects or reducing its efficacy. Always inform your doctor about any other medications or supplements you are taking:

• Cisplatin
• Fluorouracil
• Doxorubicin

Additionally, it may interact with the following conditions:

• Glomerulonephritis
• Myeloid tumors
• Leukocytosis

Warnings and Precautions:

Grafeel 300 mcg Injection may exacerbate certain conditions:

• Allergies
• Kidney or liver disease
• It is contraindicated for pregnant or breastfeeding women.
• Driving or operating heavy machinery should be avoided, as it may cause dizziness.
• Ensure adequate hydration while taking this medicine.
• Regular monitoring of bone density and blood tests is essential during treatment.
• Consult your doctor promptly if you experience any concerning symptoms.

Important Reminders:

• Keep Grafeel 300 mcg Injection out of children’s reach.
• This medicine should be administered cautiously in children.
• Consult the product leaflet for more information.
• Always check with your doctor regarding dosage and duration of treatment.

Usage Recommendations:

Follow your doctor’s recommendations for Grafeel 300 mcg Injection. Do not extend usage beyond the prescribed duration.

Storage:

Store Grafeel 300 mcg Injection at room temperature in a dry, dark place. Ensure the injection remains intact and undamaged during storage.