Colstim 300 Mcg Prefilled Syringe

Description

Colstim 300 Mcg Prefilled Syringe (Filgrastim)

Generic Name for Colstim 300 Mcg Prefilled Syringe:

The generic name for Colstim 300 mcg Prefilled Syringe is Filgrastim.

Equivalent USA Brand for Colstim 300 Mcg Prefilled Syringe (Filgrastim):

• Neupogen

About Colstim 300 Mcg Prefilled Syringe (Filgrastim)

The Colstim 300 mcg Prefilled Syringe contains Filgrastim, a human granulocyte colony-stimulating factor (G-CSF) analog. Filgrastim stimulates the growth of white blood cells and reduces the risk of infections in patients undergoing chemotherapy for cancer. Patients with blood disorders should not use this medication. It is available at major pharmacies and medical supply stores and requires a doctor’s prescription.

Manufacturer:

Colstim 300 mcg Prefilled Syringe is manufactured by Zydus Cadila Ltd., a leading pharmaceutical company.

Strength:

Each Colstim 300 mcg Prefilled Syringe contains 300 mg of Filgrastim. Other substitutes and strengths are available at various online pharmacies and medical supply stores.

Uses of Colstim 300 Mcg Prefilled Syringe (Filgrastim):

Colstim 300 mcg Prefilled Syringe is indicated for the treatment of:

• Neutropenia resulting from chemotherapy
• Bone marrow transplantation
• Peripheral progenitor cell transplantation
• Chronic neutropenia
• Neutropenia caused by radiation

Mechanism of Action of Colstim 300 Mcg Prefilled Syringe (Filgrastim):

Filgrastim is a growth factor that stimulates the bone marrow to produce white blood cells, which are essential for protecting the body from infections. Produced using recombinant DNA technology, Filgrastim controls the proliferation of committed progenitor cells and facilitates their maturation into neutrophils. It also encourages the release of neutrophils from bone marrow reserves, reducing their maturation time. This action enhances the phagocytic activity of mature neutrophils, thus helping to prevent infections. For patients receiving cytotoxic chemotherapy, Filgrastim may expedite neutrophil recovery, shortening the duration of the neutropenic phase post-chemotherapy.

Precautions Before Using Colstim 300 Mcg Prefilled Syringe (Filgrastim):

Ensure that:

• You are not allergic to Filgrastim.
• You do not have any serious medical conditions.
• Your doctor is aware of your medical history, including any pre-existing conditions, surgeries, medications, supplements, dietary habits, and lifestyle choices.

Avoid While Taking Colstim 300 Mcg Prefilled Syringe (Filgrastim):

• Avoid alcohol consumption.
• Avoid driving.
• Avoid taking medications without a prescription.

Contraindications for Colstim 300 Mcg Prefilled Syringe (Filgrastim):

Do not use Colstim 300 mcg Prefilled Syringe if you:

• Have a history of allergy or hypersensitivity.
• Have liver problems.
• Have kidney issues.
• Have a splenic rupture.
• Have acute respiratory distress syndrome (ARDS).
• Have a sickle cell crisis.
• Have a blood disorder.
• Have decreased bone density.
• Are pregnant.
• Have active infections.
• Are breastfeeding.

Inform Your Doctor If You:

• Are allergic to the syringe.
• Are consuming alcohol or other medications.
• Have liver disease.
• Have any infections.

Dosage Guidelines:

Colstim 300 mcg Prefilled Syringe contains Filgrastim, used to treat infections following chemotherapy. This medicine is available in various strengths and requires a doctor’s prescription. Consult your physician for appropriate dosage adjustments as individual age and disease severity can vary.

Adults should take Colstim 300 mcg Prefilled Syringe regularly, at a fixed time, with or without food, as instructed by their doctor. For optimal results, adhere to a consistent schedule.

Dosage Administration:

Since Colstim 300 mcg Prefilled Syringe comes in various strengths and formulations, patients should always follow their doctor’s instructions for usage. Do not self-administer or exceed the recommended duration without consulting your doctor.

Usage Instructions:

Take Colstim 300 mcg Prefilled Syringe at the same time as directed by your healthcare provider. It should be administered by a qualified healthcare professional; do not attempt to self-administer this medication.

Duration of Treatment:

Follow your doctor’s instructions regarding the use of Colstim 300 mcg Prefilled Syringe. Do not alter the dosage or duration without medical guidance.

Overdose Information:

In case of overdose symptoms, seek immediate medical assistance. Since Colstim 300 mcg Prefilled Syringe is administered by healthcare professionals, the risk of overdose is minimal. However, your physician will take emergency measures if necessary.

Missed Dose Protocol:

If a dose is missed, the healthcare provider should administer it as soon as possible. If it is nearing the time for the next scheduled dose, skip the missed dose. Do not double the dose to compensate for a missed one. Given that Colstim 300 mcg Prefilled Syringe is typically administered in a clinical setting, the likelihood of missing a dose is low.

Possible Side Effects of Colstim 300 Mcg Prefilled Syringe (Filgrastim):

• Bone pain
• Weakness
• Headaches
• Rash
• Nausea
• Increased lactate dehydrogenase levels
• Vomiting
• Elevated uric acid levels
• Oropharyngeal pain
• Hair loss
• Fatigue
• Diarrhea
• Constipation
• Reduced appetite
• Cough
• Difficulty breathing
• Abdominal pain
• Fever and chills
• Weight loss
• Swelling or inflammation of the mouth

Common Drug Interactions:

Several medications may interact with Colstim 300 mcg Prefilled Syringe, leading to adverse effects or reduced efficacy. Always discuss with your doctor if you are taking other medications or supplements to ensure effective treatment. It may interact with:

• Cisplatin
• Fluorouracil
• Doxorubicin

It is important to consult your physician for a complete list of potential drug interactions.

Storage Instructions for Colstim 300 Mcg Prefilled Syringe (Filgrastim):

Store the Colstim 300 mcg Prefilled Syringe in its original packaging at 2-8°C (36-46°F). Protect it from light and do not freeze. Keep it out of the reach of children and pets. If the expiration date has passed, do not use it. Dispose of it safely according to local regulations.