Xolnic 4 Mg Injection

Description

Xolnic 4 Mg Injection (Zoledronic Acid)

What Is The Generic Name For Xolnic 4 Mg Injection:

Zoledronic Acid is the generic version for Xolnic 4 mg Injection

Which US Brand is Equivalent To Xolnic 4 Mg Injection (Zoledronic Acid):

• Zometa

About Xolnic 4 Mg Injection (Zoledronic Acid)

Xolnic 4 mg Injection belongs to bisphosphonate class, containing an active ingredient, Zoledronic Acid, also known as Zoledronate. It is used to treat the porosity or weakening of the bones (Osteoporosis) caused mainly after menopause (postmenopausal Osteoporosis), also due to usage of steroids or other medicines, changes in hormone levels, inadequate diet intake, etc. Apart from that, Xolnic Injection can reduce the risk of breakdown of bones during cancer. It is also used to treat raised levels of calcium in the blood in people who have cancer. This medicine is also used in the treatment of Paget’s disease in which disruption of the replacement of old bone cells with new bone cells occurs.

Osteoporosis is a bone disease which occurs when the body loses too much bone (calcium) into the blood, makes too little bone, or both. As a result, bones become porous, weak, less and fragile, indicating that they may get broken easily from a minor fall or slightest trauma. Also, in severe cases, people can get bone fractures even from sneezing or small bumps. Symptoms of Osteoporosis are not visible in the early stages. Still, when the disease progresses and bones become weaker, one can observe the signs and symptoms like back pain, which may be caused by a fractured vertebra, body pain, loss of height over time, stooped posture, frequent bone fractures even in slight injuries. Various risk factors may attribute the chances of Osteoporosis which includes your age, sex, race, lifestyle, and medical and family histories, including all the drugs treatments a patient is going through.

Etiology/ Causes of the disease include:

• Imbalanced hormone levels like reduction in estrogen levels, decrease in sex hormones, increased levels of thyroid hormone, or overactive parathyroid and adrenal glands.
• Low calcium intake reduces bone density, which increases the risk of fractures.
• Bad eating habits weaken bone in both men and women.
• Gastrointestinal surgeries that help you lose weight limits the amount of surface area available to absorb nutrients, including calcium which then can lead to Osteoporosis.
• Long-term use of oral or parenteral steroids like prednisolone and cortisone intervene with the bone-rebuilding process leading to Osteoporosis. It has also been associated with medications used to combat or prevent Seizures, Gastric reflux, Cancer, Immunosuppressants, etc.
• The risk of Osteoporosis is higher in patients who have medical problems like Celiac disease, inflammatory bowel disease (IBD), Kidney or liver disease, Cancer, Lupus, Multiple myelomas, Rheumatoid arthritis, etc.
• Lousy lifestyle and no exercise can elevate the symptoms of Osteoporosis.
• Xolnic 4 mg Injection may be used just as a single injection, or you may need regular doses to treat your underlying condition. You may also need to drink plenty of water before the Injection, to avoid dehydration. It may take several days to months to get the full benefits of the drug. This Injection is a part of the drug regimen, but a complete treatment program may also include a healthy diet and optimum calcium intake with vitamin supplements and proper exercise.
• Xolnic 4 mg Injection is found to be safe and effective medicine and known to have various mild side effects which can be reversed by discontinuation of the drug. This Injection is readily available with all the leading pharmacies, drugstores, & medical supply stores. Moreover, this medication should be taken on doctor’s prescription-only and should be administered by doctors or nurses only.

Manufacturer:

Khandelwal Laboratories Pvt. Ltd. is the primary pharmaceutical company that manufactures Xolnic 4 mg Injection.

Strength:

Xolnic 4 mg Injection contains an active constituent, Zoledronic Acid/ Zoledronate weighing 4 mg w/v. This medicine is easily available with all the leading pharmacies, drugstores, and medical supply stores.

What Are The Uses Of The Xolnic 4 Mg Injection (Zoledronic Acid):

Xolnic 4 mg Injection is used for the treatment in the following conditions:

• Postmenopausal Osteoporosis (postmenopausal condition, in which bone becomes porous and fragile due to desorption of calcium from bone)
• Hypercalcemia (high levels of calcium in the blood due to desorption of bone)
• Paget’s disease (disruption of the replacement of old bone tissue with new bone tissue)

How Xolnic 4 Mg Injection (Zoledronic Acid) Works:

Xolnic 4 mg Injection has an active ingredient, Zoledronic Acid, which is a bisphosphonate. This medicine acts by suppressing the activity of osteoclasts, the cells present in the bone itself and responsible for desorption of calcium from bones which destroy bone only. This injection, however, strengthens the bones & minimizes the risk of fractures.

Before You Use Xolnic 4 Mg Injection (Zoledronic Acid):

Make certain that:

• You are not having some severe Disease
• You are not sensitive to Zoledronic Acid
• You must update your doctor vis-à-vis your medical histories like your pre-existing disease, Medications & surgeries, supplements, Food Habits, lifestyle, and the rest.

What Should You Avoid While Taking Xolnic 4 Mg Injection (Zoledronic Acid):

• You should avoid driving
• You should avoid taking alcohol
• You should avoid smoking
• You should avoid taking Medicines without prescriptions

When Not To Use Xolnic 4 Mg Injection (Zoledronic Acid):

You should not take Xolnic 4 mg Injection if you:

• Have ever noticed any Allergy/Hypersensitivity
• Have liver problems
• Have kidney problems
• Have thyroid or parathyroid disorders
• Have severe bone, joint or muscle pain
• Have Flu-like symptoms
• Are pregnant
• Have any kind of infection
• Are breastfeeding

Tell Your Doctor If You:

• Have an Allergy to the Injection or its contents
• Are taking Alcohol or Other Drugs
• Have Liver/ Kidney disease
• Have hypercalcaemia or hypocalcaemia
• Have any hormonal problems
• Have any medical history
• Are taking any steroids or other drugs which can affect its absorption or increase toxicity
• Have any type of infection

Dosage:

Xolnic 4 mg Injection contains an active ingredient, Zoledronic Acid, which is used to treat or prevent the weakening of the bones (Osteoporosis). This medicine is readily available with all the leading pharmacies, drugstores, and medical supply stores; though, this medication should be taken on doctor’s prescription only. The patient must discuss with the medical doctor for an alteration of dosage & time of medicine, knowing the fact that the severity of the disease can vary from person to person. Your doctor can best judge this adjustment.

Adults are advised to take Xolnic 4 mg Injection at a fixed time with or without food. An injection can be given via a vein (intravenous) under strict supervision of a doctor or nurse. The usual dosage for adults is given below:

• Postmenopausal Osteoporosis: 4 mg once a year with sufficient hydration.
• Hypercalcemia: 4 mg given as a single dose.
• Paget’s Disease: 5 mg as a single dose.

This Injection can also be given as a single injection, or you may need regular doses to treat your underlying condition. You may also need to drink plenty of water before the Injection, to avoid dehydration. It may take several days to months to get the full benefits of the drug.

Missed Dose:

In case of missing a dose, contact your doctor to know what to do. Do not take an extra dose of the Injection, without consulting your doctor. You should not take extra doses to compensate for the missed one.

Side Effects Of Xolnic 4 Mg Injection (Zoledronic Acid)

Xolnic 4 mg Injection can cause some common side effects. Some of these may not need any medical attention, while others can be serious. These side effects can occur at any time and may need medical intervention.

• Back pain
• Pain in joints and muscles
• Swelling of the hands, ankles, or feet
• Feeling tired or weak
• Headache
• Flu-like symptoms
• Nausea
• Vomiting
• Dizziness
• Stomach pain
• Abdominal pain
• Redness, swelling, or pain at the injection site
• Fever
• Rash
• Itching

Some serious side effects may require immediate medical attention. These include:

• Severe allergic reaction (rash, itching, difficulty breathing, swelling of the face, lips, or tongue)
• Signs of kidney problems (changes in the amount of urine, swelling, or difficulty urinating)
• Severe bone, joint, or muscle pain
• Signs of low calcium levels (muscle spasms, twitching, or seizures)
• Signs of infection (fever, chills, body aches)
• Unusual bleeding or bruising

Storage Conditions For Xolnic 4 Mg Injection (Zoledronic Acid):

Xolnic 4 mg Injection should be stored at room temperature, away from light and moisture. Keep all medicines out of reach of children and pets. Do not store the Injection in the bathroom. Keep the Injection in its original packaging until use. Do not freeze the Injection. In case of expired or unused Injection, please consult your local waste disposal company or your pharmacist for proper disposal.